TB-500 - 10mg
TB-500 is a synthetic peptide that corresponds to the active region of the naturally occurring thymosin beta-4 protein, a key regulator of cell migration, differentiation, and repair. It is recognized for its potential to support wound healing, tissue regeneration, and recovery in experimental models. TB-500 is of interest in studies involving muscle repair, angiogenesis, and anti-inflammatory effects.
A synthetic fragment of thymosin beta-4 (Tβ4) modeled for laboratory research.
TB-500 is a synthetic peptide that corresponds to the active region of the naturally occurring thymosin beta-4 protein, a key regulator of cell migration, differentiation, and repair. It is recognized for its potential to support wound healing, tissue regeneration, and recovery in experimental models. TB-500 is of interest in studies involving muscle repair, angiogenesis, and anti-inflammatory effects.
In laboratory settings, TB-500 is thought to function by upregulating actin-binding proteins, enhancing cell motility, and promoting the formation of new blood vessels. This may facilitate accelerated tissue repair, improved flexibility, and reduced recovery time in injury models. Its multifaceted biological activity has made it a focus for research into both acute and chronic injury recovery, as well as degenerative disease repair pathways.
Titan research and immune system function
Tissue Regeneration:
TB-500 is studied for its ability to promote regeneration of damaged muscle, ligament, and tendon tissue in experimental injury models.
Wound Healing Research:
Research examines its effects on accelerated epithelialization and reduced scarring in skin and organ injury studies.
Angiogenesis & Vascular Growth:
TB-500 may stimulate new blood vessel formation, improving circulation and nutrient delivery to damaged tissues.
Inflammation Modulation:
Studies investigate its potential to reduce inflammatory markers and facilitate recovery in inflamed tissues.
Post-Injury Recovery:
Models explore its possible benefits in shortening recovery times and improving functional outcomes after trauma.
Titan research and immune system function
Actin Cytoskeleton Regulation:
TB-500 enhances actin polymerization, supporting cell movement, structural integrity, and repair processes.
Cell Migration & Differentiation:
Its influence on cellular motility and differentiation is relevant in regenerative medicine research.
Anti-Inflammatory Pathways:
TB-500 may downregulate pro-inflammatory cytokines while supporting healing and repair.
(1) Goldstein, A. L., & Hannappel, E. (2008). Thymosin beta-4: a multi-functional regenerative peptide. → Describes TB-500’s role in angiogenesis, cell migration, and wound healing. [Annals of the New York Academy of Sciences, 1194(1), 170–177]
(2) Bock-Marquette, I., et al. (2004). Thymosin β4 activates integrin-linked kinase and promotes cardiac cell migration and survival. → Showed accelerated tissue regeneration and angiogenesis in cardiac injury models.
(3) Philp, D., et al. (2003). Thymosin beta-4 promotes wound healing and tissue regeneration. → Animal studies showed enhanced cell migration and repair within days to weeks.
The chart illustrates the effects of TB-500 (Thymosin Beta-4) on tissue repair over a four-week period, drawing from animal data with inferred implications for human use. At week 1, there is an estimated 10% improvement in tissue regeneration, showing an initial but modest benefit. By week 2, the improvement climbs to 30%, suggesting that TB-500 begins to exert more noticeable regenerative effects with continued exposure.
By week 4, the estimated improvement reaches 55%, highlighting a strong cumulative impact on tissue repair and recovery. This steep upward trend indicates that TB-500 may play a significant role in models of accelerated healing, cellular repair, and regeneration when studied over extended durations.
Form:
Lyophilized Powder
Storage (unreconstituted):
- Store at 2–8 °C (refrigerated), protected from light.
- For long-term storage, keep at –20 °C.
- Avoid repeated freeze–thaw cycles.
Reconstitution:
- Reconstitute with sterile water for injection or 0.9% NaCl immediately prior to use. Use aseptic technique.
Storage (after reconstitution):
- Store at 2–8 °C.
- Use within 7–10 days.
- Discard any unused solution after this period.
- Handle under sterile conditions.
- Do not shake vigorously (may cause peptide denaturation).
- Inspect visually for particulate matter or discoloration before use.
Issued for quality verification of tested material.
Feedback highlighting proven outcomes and reliability.
