SEMAX - 30mg
Semax is a synthetic peptide derived from a fragment of adrenocorticotropic hormone (ACTH 4–10) with the addition of a C-terminal Pro-Gly-Pro sequence. It is primarily recognized for its potential neuroprotective, nootropic, and neuromodulatory effects. Structurally designed to resist enzymatic degradation, Semax is of interest in experimental models for cognitive enhancement, stroke recovery, neurodegenerative conditions, and mood regulation.
A synthetic analog of adrenocorticotropic hormone (ACTH) fragments, modeled for laboratory research.
Semax is a synthetic peptide derived from a fragment of adrenocorticotropic hormone (ACTH 4–10) with the addition of a C-terminal Pro-Gly-Pro sequence. It is primarily recognized for its potential neuroprotective, nootropic, and neuromodulatory effects. Structurally designed to resist enzymatic degradation, Semax is of interest in experimental models for cognitive enhancement, stroke recovery, neurodegenerative conditions, and mood regulation.
Semax functions by modulating neurotrophic factors, neurotransmitter metabolism, and antioxidant defenses. In laboratory studies, it has been shown to increase the expression of brain-derived neurotrophic factor (BDNF), regulate dopaminergic and serotonergic systems, and reduce oxidative stress markers. Through its multifaceted influence on neural and systemic processes, Semax may support neuronal survival, cognitive resilience, and recovery in various experimental contexts.
Titan research and immune system function
Neuroprotection Models:
Semax is studied for its potential to protect neurons from ischemic damage, oxidative stress, and excitotoxicity, especially in stroke and brain injury models.
Cognitive Function & Learning:
Research explores its influence on memory, learning speed, and mental clarity, with potential applications in aging-related cognitive decline models.
Mood & Stress Regulation:
Studies examine Semax’s role in stabilizing mood and modulating stress-induced neurochemical imbalances.
Neurodegenerative Research:
Investigators assess its possible role in slowing or reversing cellular damage in models of Alzheimer’s, Parkinson’s, and other neurodegenerative conditions.
Vision & Sensory Recovery:
Some experimental work investigates Semax’s potential to aid recovery of visual and sensory functions following injury or degeneration.
Titan research and immune system function
Neurotrophic Factor Stimulation:
Semax has been shown to increase BDNF levels, enhancing neuronal plasticity and resilience.
Neurotransmitter Balance:
It modulates dopamine, serotonin, and glutamate pathways, making it relevant in cognitive and behavioral neuroscience studies.
Antioxidant & Anti-Inflammatory Effects:
Laboratory findings suggest Semax reduces pro-inflammatory cytokines and oxidative damage markers in neural tissue.
(1) Kaplan, A. Y., et al. (1997). Semax improves short-term memory and attention in healthy humans. → Reported improvements in EEG focus and attention levels within the first week of use.
(2) Dolotov, O. V., et al. (2006). Semax increases BDNF and TrkB expression in hippocampus. → Demonstrated a rise in neurotrophic factors within 2–4 weeks, enhancing memory and neuron resilience. [PubMed ID: 16996037]
(3) Lebedeva, I., et al. (2018). Effects of Semax on the default mode network and executive function. → Human fMRI data confirmed enhanced neural activation and improved executive function by week
The chart shows the cognitive and neuroprotective benefits of Semax over a four-week period, combining both human and preclinical data. In the first week, there was an estimated 10% improvement, demonstrating an early measurable effect. By the second week, this benefit increased to 18%, reflecting a steady enhancement in both cognitive function and neuroprotection.
By the fourth week, the improvement rose substantially to 30%, suggesting that Semax produces more pronounced effects with continued use. This progression highlights its potential as a research compound in supporting memory, learning, and neuroprotection, particularly in models of cognitive decline and stress.
Form:
Lyophilized Powder
Storage (unreconstituted):
- Store at 2–8 °C (refrigerated), protected from light.
- For long-term storage, keep at –20 °C.
- Avoid repeated freeze–thaw cycles.
Reconstitution:
- Reconstitute with sterile water for injection or 0.9% NaCl immediately prior to use. Use aseptic technique.
Storage (after reconstitution):
- Store at 2–8 °C.
- Use within 7–10 days.
- Discard any unused solution after this period.
- Handle under sterile conditions.
- Do not shake vigorously (may cause peptide denaturation).
- Inspect visually for particulate matter or discoloration before use.
Issued for quality verification of tested material.
Feedback highlighting proven outcomes and reliability.
